These are identical as can be seen from the following worked example where total cholesterol is 4.9, HDL is 0.06 and Triglyceride is 1.51 mmol/l:
Using ESH Task Force version we get: LDL cholesterol = 4.9 - 0.06 -(0.45 X 1.51) = 4.1605 mmol/l
Using the Heartwatch version we get: LDL cholesterol = 4.9 - 0.06 - (1.51/2.2) = 4.1536 mmol/l
Here is the description of the above as it appears in the ESH Task Force document:
Most laboratories measure cholesterol, triglycerides and the part of cholesterol carried in HDL, namely HDL cholesterol. With these three measurements, the part of cholesterol carried in LDL can be calculated according to the Friedewald formula: In mmol/l-1:
LDL cholesterol = total cholesterol - HDL cholesterol - (0.45 x triglycerides)
In mg/dl-1:
LDL cholesterol = total cholesterol - HDL cholesterol - (0.2 x triglycerides)
The calculation is based on the assumption that triglycerides are less than 5mmol/l-1 (450mg/dl-1).
The accuracy of this estimation of LDL cholesterol can be reduced due to a summation of possible analytical errors in the various lipid measurements. For the time being, however, the Friedewald calculation is cheaper and more reliable estimation of LDL cholesterol than commercially available direct measurements of LDL based on immunoseparation[383].
Reference:
[383] Yu HH, Ginsburg GS, Harris N, Rifai N. Evaluation and clinical application of the direct low-density lipoprotein cholesterol assay in normolipidemic and hyperlidemic adults.
Am J Cardiol 1997; 80: 1295-9.
Here is the description of the above as it appears on page 19 of the Heartwatch Reference Guide, which was supplied on CD to participating practices:
LDLc can be calculated, if the result is not available from the laboratory by using the Friedwald formula below:
LDL Cholesterol = Total Cholesterol - HDL - (Fasting TG divided by 2.2)
Note: Fasting TGs are necessary if TGs greater than 4.